Fig. 1: AC073352.1 expression is upregulated and associated with poor outcomes in BC. | Cell Death & Disease

Fig. 1: AC073352.1 expression is upregulated and associated with poor outcomes in BC.

From: A novel long non-coding RNA AC073352.1 promotes metastasis and angiogenesis via interacting with YBX1 in breast cancer

Fig. 1

a A flowchart showing the selection of lncRNA AC073352.1 from the LncRNA microarray and TCGA database in BC. A heatmap representation of 10 overlapping lncRNA for gene expression profiles of 6 BC tissues and paired adjacent normal tissues in LncRNA microarray (fold change >2 or <0.5, p < 0.001). b Kaplan–Meier analyses of the correlation between AC073352.1 RNA levels and the overall survival rate of patients with BC, using TCGA data. Patients were stratified for the analysis using the median. c–e ISH analysis detecting AC073352.1 expression (red) in BC tissue (n = 137) and adjacent normal tissues (n = 67). Representative images from c two BC cases and d adjacent normal tissue are shown (magnification: ×200). e Statistical analysis was assessed by t test. ***p value < 0.001.

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