Fig. 1: Identification of differentially expressed lncRNAs.

a, b Hierarchical clustering heatmap (a) and volcano plots (b) of TCGA and GSE96574 showing the differentially expressed lncRNAs between ccRCC samples and normal samples. c Comparison of the differentially upregulated or downregulated lncRNAs in the two datasets. d A Circos plot was used to show the differentially expressed lncRNAs (log2 fold change (FC) | > 1, P < 0.05). The inner circle shows the downregulated lncRNAs (purple dots) and the second circle identifies the upregulated lncRNAs in ccRCC tissues (red triangles) according to GSE96574. The third circle shows the downregulated lncRNAs (purple dots) and the fourth circle identifies the upregulated lncRNAs in ccRCC tissues (red triangles) according to TCGA. The outside circle represents the overlap of upregulated (pink dot) or downregulated lncRNAs (blue dots).