Fig. 8: lncRNA RCAT1 knockdown suppresses tumor proliferation and metastasis in vivo.

a–c The photos (a), growth curve (b), and weight (c) of the xenograft tumors. Scale bar, 1 cm. d H&E staining of the xenograft tumors. IHC results of Ki67 level and E2F2 level in xenograft tumor tissues. Scale bar, 100 μm. e Representative images of lung metastatic nodules and H&E staining of lungs isolated from nude mice (n = 5 for each group). Scale bar, 100 μm. f The numbers of metastatic nodules in the lungs of nude mice were calculated and compared. Scare bar = 50 μm (***P < 0.001).