Fig. 3: Exosomes derived from WERI-Rb1 cells were engulfed by tumor cells and promoted the growth of retinoblastoma. | Cell Death & Disease

Fig. 3: Exosomes derived from WERI-Rb1 cells were engulfed by tumor cells and promoted the growth of retinoblastoma.

From: Retinoblastoma cell-derived exosomes promote angiogenesis of human vesicle endothelial cells through microRNA‐92a-3p

Fig. 3

A Representative macroscopic appearance of tumors after subcutaneously injection PBS or exosomes for 21 days. B The tumor volume growth curve in the xenotransplantation model (n = 14, *P < 0.05, **P < 0.01). C PKH26-labeled exosomes (red) were internalized by cells from tumor tissues after 10 days after exosomes injection. DAPI was used to stain the nuclei. Bar = 25 μm. D Ultrasound analysis showed that blood flow was increased by exosome injection. E Quantification of blood flow in tumors (n = 9, *P < 0.05).

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