Fig. 4: Exosomes derived from WERI-Rb1 cells increase retinoblastoma angiogenesis in vivo. | Cell Death & Disease

Fig. 4: Exosomes derived from WERI-Rb1 cells increase retinoblastoma angiogenesis in vivo.

From: Retinoblastoma cell-derived exosomes promote angiogenesis of human vesicle endothelial cells through microRNA‐92a-3p

Fig. 4

A Immunofluorescence analysis of CD31-positive cells showed that the capillary density in the EXO-injected group was increased. Bar = 200 μm. B Quantification of the CD31-positive area (%) in the tumors (n = 5, *P < 0.05). C Immunofluorescence analysis of the isolectin positive areas. Bar = 500 μm. D Quantification of isolectin positive area (blood vessel density, %) in the tumors (n = 7, *P < 0.05). E Western blot images showing the protein levels of CD31, VCAM1, and ICAM1 in tumors from the PBS-injected group and EXO-injected group. F Relative quantification of protein expression in tumors (n = 6, *P < 0.05).

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