Fig. 6: Overexpression of miR-92a-3p in HUVECs enhances angiogenesis in vitro. | Cell Death & Disease

Fig. 6: Overexpression of miR-92a-3p in HUVECs enhances angiogenesis in vitro.

From: Retinoblastoma cell-derived exosomes promote angiogenesis of human vesicle endothelial cells through microRNA‐92a-3p

Fig. 6

A, B HUVECs were transfected with synthetic mimic control (NC-m) or miR-92a-3p mimic (miR-92a-3p-m). The mRNA levels of miR-92a-3p, VCAM1, ICAM1, IL-1, IL-6, IL-8, and MCP-1 were increased (n ≥ 4, *P < 0.05, **P < 0.01, ***P < 0.001). C Wound-healing assay revealed that miR-92a-3p could enhance the migration rate of the HUVECs. D Relative quantification of HUVEC migration 24 h after the wound scratch (n = 4, *P < 0.05). E, F Quantitative evaluation of the number of junctions after transfection of the HUVECs with NC-m or miR-92a-3p (24 h, n = 9, *P < 0.05).

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