Fig. 1: Deletion of Fto in the cerebral cortex does not change development of neural progenitors. | Cell Death & Disease

Fig. 1: Deletion of Fto in the cerebral cortex does not change development of neural progenitors.

From: Distinct roles of Fto and Mettl3 in controlling development of the cerebral cortex through transcriptional and translational regulations

Fig. 1

A–G Immunohistochemistry (A–C) and cell counting (D–G) in the cerebral cortex of E13.5 F-cKO mice. The numbers of BrdU+ and Ki67+ cells, and Sox2+ and Tbr2+ neural progenitors were not changed in E13.5 F-cKO cortices, compared to controls (Ctrl). H–N Immunohistochemistry (H–J) and cell counting (K–N) in the cerebral cortex of E15.5 F-cKO mice. The numbers of BrdU+ and Ki67+ cells, and Sox2+ and Tbr2+ neural progenitors were not changed in E15.5 F-cKO cortices, compared to the Ctrl. Scale bars: 25 μm. Error bars indicate the SEM (six independent samples). P values were calculated by Student’s t-test between Ctrl and F-cKO. P values: n.s.: non-significant.

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