Fig. 2: Cortical-specific deletion of Mettl3 causes neurogenesis defects in E15.5 cortex. | Cell Death & Disease

Fig. 2: Cortical-specific deletion of Mettl3 causes neurogenesis defects in E15.5 cortex.

From: Distinct roles of Fto and Mettl3 in controlling development of the cerebral cortex through transcriptional and translational regulations

Fig. 2

A–C The number of BrdU+ cells (red) was not changed, the number of Ki67+ cells (green) was increased in M-cKO cortices, compared to controls (Ctrl). D–G The number of Sox2+ neural progenitors was not changed, the number of Tbr2+ neural progenitors was increased in M-cKO cortices, compared to the Ctrl. H–K The numbers of Tbr1+ and Satb2+ neurons were reduced in M-cKO cortices, compared to the Ctrl. Scale bars: 70 μm. Error bars indicate the SEM (six independent samples). P values were calculated by Student’s t-test between Ctrl and M-cKO. P value: **P < 0.01; ***P < 0.001; n.s.: non-significant.

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