Fig. 5: Altered translation efficiency (TE) caused by Mettl3 and Fto knockout.

A–C Numbers of mRNAs with low-TE and high-TE in E15.5 control (Ctrl), F-cKO, and M-cKO cortices detected by Ribo-seq and RNA-seq. D, E Distributions of significantly differentially expressed mRNAs in three intervals of high-, medium-, and low-TE in the six-quadrant diagram. The red box illustrates mRNAs with most significantly altered TE.