Fig. 6: Altered expression of major genes expressed in RGCs and IPs in M-cKO and F-cKO cortices.

A Numbers of RGC genes showed different (diff genes), none different (non-diff genes), up- and downexpression in F-cKO and M-cKO cortices detected by Ribo-seq. B GO analyses of upregulated (red) and downregulated (blue) RGC genes in M-cKO cortices. C Numbers of IP genes showed different, none different, up- and downexpression in F-cKO and M-cKO cortices detected by Ribo-seq. D GO analyses of upregulated (red) and downregulated (blue) RGC genes in M-cKO cortices. E, F Integrative Genomics Viewer (IGV) images of expression patterns (left) and expression quantifications (right) of Fabp7, Gpm6b, Gpm6a, Cdk6 (E), and Ccnb1, Tcf4, Epha4, Nrp1 (F) in E15.5 control (Ctrl), F-cKO, and M-cKO cortices detected by RNA-seq and Ribo-seq. Error bars indicate the SEM (three independent samples). P values were calculated by Student’s t-test between Ctrl and F-cKO or Ctrl and M-cKO. P values: *P < 0.05; **P < 0.01; ***P < 0.001.