Fig. 3: RBM15 is elevated in SARS-CoV-2 infection and positively correlated with the severity of the COVID-19. | Cell Death & Disease

Fig. 3: RBM15 is elevated in SARS-CoV-2 infection and positively correlated with the severity of the COVID-19.

From: RBM15-mediated N6-methyladenosine modification affects COVID-19 severity by regulating the expression of multitarget genes

Fig. 3

A m6A regulators were selected from microarray data and then analyzed. Heatmap showing the expression of regulators in group S vs N. B Box plot showing gene expression results obtained using qRT-PCR (N: 20 healthy controls, M: 19 mild patients, S: 20 severe patients, *P < 0.05, **P < 0.01, and ***P < 0.001). C RBM15 and YTHDF2 expression levels in HuT 78 cells co-cultured with activated THP-1 cells were measured after being treated with HA and S proteins separately for 0, 6, 12, 24, and 36 h. Data were shown as means ± SD (n = 3, *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001).

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