Fig. 6: ROS may be the cause of abnormal FTO levels and m6A disorder in aged ovarian granulosa cells.
From: The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging

A Western blot analysis showed that FTO was downregulated with increasing levels of hydrogen peroxide. B RT-PCR showed the downregulation of FTO by hydrogen peroxide. C The effect of hydrogen peroxide on the expression of FOS in GCs was shown by RT-PCR. Performed three times. The error bars indicate SD; *p < 0.05, ***p < 0.001.