Fig. 3: TP73 N-terminal Expression in Human Tissue.
From: Tissue-specific expression of p73 and p63 isoforms in human tissues
A Sina plots of TP73 N-terminal exon counts for select human tissue types from the GTEx dataset. Exon counts are normalized by exon length and sequencing depth and plotted on a log2 scale (normalized counts + 0.01). Each red dot indicates the median value of the population. Tissues are grouped and shaded by the following: p73-High/p63-High (yellow), p73-High (purple), and p63-High (green). The average TP73 gene expression (units = TPM) of each GTEx tissue is listed below its respective plot. B Heatmaps (left-sided) of the mean number of exon junction-spanning reads connecting exon 3 or exon 3′ to exon 4 (E3/3′-E4) and the mean number of junction-spanning reads between exons 5–10 (E5–E10) for both TP73 and TP63. Tissues are grouped and shaded as described in Part A. The right-sided heatmap shows the ratio of E3/E3′–E4 to E5–E10 junction-spanning reads for TP73 and TP63.
