Fig. 4: Differential TP73 TSS usage in human tissue. | Cell Death & Disease

Fig. 4: Differential TP73 TSS usage in human tissue.

From: Tissue-specific expression of p73 and p63 isoforms in human tissues

Fig. 4

A Genome browser view of the 5′ end of the TP73 genomic locus showing the read density of 5′-end RNA-seq (RAMPAGE) for select human tissue from the ENCODE Project. RAMPAGE peaks (i.e., TSS) were identified using the ENCODE standard RAMPAGE pipeline and are marked with an asterisk. B Genome browser view of TP73 exon 4 showing aligned reads from 5′-end (RAMPAGE, red-colored reads) and poly-A (GTEx, blue-colored reads) RNA-seq performed on the same skin, esophagus, and vagina samples. The thin gray lines annotate reads aligning to the junctions between exon 3 or 3′ and exon 4. The methionine within exon 4 (green colored, marked with an arrowhead) is the putative start codon of E4p73.

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