Fig. 3: WFDC21P and STAT3 levels are increased in NSCLC.

a qRT-PCR analysis for WFDC21P level in NSCLC tissues and corresponding para-carcinoma tissues (n = 16). Data are expressed as median (interquartile range). **P < 0.01; Mann–Whitney U test. b qRT-PCR analysis for WFDC21P level in A549, H1299, H1975, and HBE cells. Data are expressed as mean ± SD for triplicate experiments. **p < 0.01; ANOVA test. c Western blot detection of STAT3 in A549, H1299, H1975, and HBE cells. d qRT-PCR analysis of STAT3 expression in NSCLC tissues and corresponding para-carcinoma tissues (n = 16). Data are expressed as median (interquartile range). **P < 0.01; Mann–Whitney U test. e–g Pearson′s correlation analysis of miR-4293 expression and WFDC21P expression (n = 16, **P = 0.015) (e), miR-4293 expression and STAT3 expression (n = 16, **P < 0.01) (f), WFDC21P expression and STAT3 expression (n = 16, **P < 0.01) (g).