Fig. 1: OGT is upregulated in the kidney of CKD mice. | Cell Death & Disease

Fig. 1: OGT is upregulated in the kidney of CKD mice.

From: Silencing of O-linked N-acetylglucosamine transferase ameliorates hypercalcemia-induced neurotoxicity in renal failure by regulating EZH2/KLF2/CXCL1 axis

Fig. 1

A Bodyweight of mice in each group from 0 to 7 days. B SCr, and BUN contents in serum. C HE staining for kidney tissue damage. D The protein expression of OGT in kidney tissues of each group detected by Western blot analysis. E Escape latency and step-down tests were used to observe the changes of nerve function in CKD mice. F the Calcium content in brain tissues of mice in each group. G TUNEL staining was used to detect neuronal apoptosis in brain tissues. *p < 0.05. vs. the control group (mice on a standard diet). n = 8. The experiment was repeated 3 times independently.

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