Fig. 2: ALCAP2 arrests the cell cycle and promotes the apoptosis of LUAD cells. | Cell Death & Disease

Fig. 2: ALCAP2 arrests the cell cycle and promotes the apoptosis of LUAD cells.

From: ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L

Fig. 2

A, B Flow cytometry assay of LUAD cell lines. The cells were harvested at 24 h after treatment with or without ALCAP2 and stained with PI. The percentage of cells in each cell cycle phase is shown in the inset of each panel. C, D Flow cytometry assay of A549 and H1299 cells treated with or without ALCAP2. Cells harvested at 24 h after transfection and stained with Annexin V-FITC and PI. The right histogram panel shows the statistics of the number of apoptotic cells in each group. The data were presented as the mean ± SD of three measurements. NS: no significance, *P < 0.05; **P < 0.01; ***P < 0.001.

Back to article page