Fig. 3: ALCAP2 suppresses the migration and invasion of LUAD cells. | Cell Death & Disease

Fig. 3: ALCAP2 suppresses the migration and invasion of LUAD cells.

From: ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L

Fig. 3

A, B Representative images showing the results of Transwell cell migration and invasion assays of A549 and H1299 cells treated with or without ALCAP2. C The protein expression of N-cadherin, E-cadherin, vimentin, MMP9, Akt, p-Akt, H2AX, cyclin D1, PARP and survivin in A549 and H1299 cells treated with or without ALCAP2 as determined by western blot analysis. The data were analysed by unpaired Student’s t-test, **P < 0.01, and ***P <0.001 vs the control.

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