Fig. 6: The effects of ALCAP2 on LUAD cells could be reversed by knockdown of NEDD4L. | Cell Death & Disease

Fig. 6: The effects of ALCAP2 on LUAD cells could be reversed by knockdown of NEDD4L.

From: ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L

Fig. 6

A The viability of si-NEDD4L H1299 cells after treated with ALCAP2 was determined by MTT assay. B, D Flow cytometry assay to detect the cell cycle and apoptosis of H1299 cells and si-NEDD4L H1299 cells treated with ALCAP2. C The protein expression of β-catenin, NEDD4L, cyclin D1 and survivin. The data were presented as the mean ± SD of three measurements. NS no significance, ***P < 0.001.

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