Fig. 6: HDAC2 knockout promoted tumor lymphocyte infiltration. | Cell Death & Disease

Fig. 6: HDAC2 knockout promoted tumor lymphocyte infiltration.

From: Histone deacetylase 2 knockout suppresses immune escape of triple-negative breast cancer cells via downregulating PD-L1 expression

Fig. 6

A, B The Balb/c mice were sacrificed at 33 days after WT and HDAC2-KO cells’ (4T-1) inoculation, and tumors of each group were isolated, and the infiltration of lymphocytes was analyzed by flow cytometry using the indicated antibodies. Gating strategy (A) and representative plots (KO group) are shown. Proportions of CD45+, CD3+, CD3+CD4+, CD3+CD4+FOXP3+, CD3+CD8+, CD3+CD8+CD69+, and CD3+ CD8+CD107+ T cells in tumors of each group (B, n = 5).

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