Fig. 2: Silencing hsa_circ_0007813 suppressed proliferation, migration, and invasiveness potentials of bladder cancer cells in vitro. | Cell Death & Disease

Fig. 2: Silencing hsa_circ_0007813 suppressed proliferation, migration, and invasiveness potentials of bladder cancer cells in vitro.

From: Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation

Fig. 2

A At 48 h after siRNA (si-circ-1, si-circ-2, and si-circ-3) transfection, hsa_circ_0007813 expression levels in both T24 and UM-UC-3 were analyzed by qRT-PCR (N = 3, Kruskal–Wallis test). At 24 h after siRNA transfection, B, C CCK-8 assays (N = 3, Kruskal–Wallis test) and D colony formation assays (scale bar represents 1 cm) were used to assess the proliferation ability of cells. E Wound healing assays (scale bar represents 1000 μm) were used to assess the migration ability of cells. F Transwell assays (scale bar represents 100 μm) were used to assess the invasiveness of cells. All error bars in the figures indicated the standard deviation of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001.

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