Fig. 2: Nueral crest differentiation of SOX10-knockout hiPSCs. | Cell Death & Disease

Fig. 2: Nueral crest differentiation of SOX10-knockout hiPSCs.

From: SOX10 ablation severely impairs the generation of postmigratory neural crest from human pluripotent stem cells

Fig. 2

A The morphology change during neural crest differentiation from WT and SOX10-knockout cell lines was detected under phase-contrast microscopy. Scale bar, 250 μm. B Sphere formation and attachment for detection of migration ability in day 7 differentiated WT and KO cells. Scale bar, 300 μm. C The number of spheres, diameter of spheres, and migration distance between 24 h and 48 h after attachment was calculated and compared. n = 3 biological replicates. The results are the mean ± SD. **p < 0.01.

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