Fig. 5: Characterization of day-3 and day-5 differentiated cells in WT and KO groups. | Cell Death & Disease

Fig. 5: Characterization of day-3 and day-5 differentiated cells in WT and KO groups.

From: SOX10 ablation severely impairs the generation of postmigratory neural crest from human pluripotent stem cells

Fig. 5

A Expression of neural epithelial cell markers PAX6 and SOX1 in day-3 differentiated cells in WT and KO groups was detected by immunostaining. Scale bar, 100 μm. B The number of PAX6+/SOX1+ cells in day-3 differentiated cells was calculated and compared. C Expression of neural epithelial cell markers SOX10 and SOX9 in day-5 differentiated cells in WT and KO groups was detected by immunostaining. Scale bar, 100 μm. D The number of SOX10+ and SOX9+ cells in day-5 differentiated cells was calculated and compared, respectively. n = 5 biological replicates. Columns represent the mean ± SD. **p < 0.01.

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