Fig. 1: PPFIBP1 expression and its correlation with invasion and survival in glioma patients.
From: PPFIBP1 induces glioma cell migration and invasion through FAK/Src/JNK signaling pathway
A Top: representative MRI images of patients with LGG and GBM. Middle and bottom: low and high magnification of glioma tumor sections of patient stained with a PPFIBP1 antibody. B PPFIBP1 expression levels in glioma specimens from 47 glioma patients. Statistical difference between LGG noninvasive, LGG invasive, and GBM was evaluated with Fisher’s exact test. C Kaplan–Meier curves show the overall survival of 77 GBM patients, of which 38 are with high level of PPFIBP1 and 39 are with low level of PPFIBP1. Data were obtained from GEO database (GSE4271). D The boxplot shows the expression levels of PPFIBP1 in patients with different grades of the same data set from GEO database (GSE4271), P value is determined by Wilcoxon signed-rank test. The figures are representative data from at least three independent experiments.
