Fig. 7: The relative expression level of ZNFTR, ATF3, ZNF24, and VEGFA in PC samples.
From: LncRNA ZNFTR functions as an inhibitor in pancreatic cancer by modulating ATF3/ZNF24/VEGFA pathway
A The relationship between ATF3 and ZNFTR (green) or ZNF24 (blue), ZNF24, and ZNFTR (green) or VEGFA (purple) in PC tissues were analyzed by Pearson’s correlation respectively. B Pearson’s correlation analysis and chi-square test identified a positive association between ZNFTR and ZNF24 in the PC samples. The chi-square test identified a negative association between ZNFTR and VEGFA in the PC samples. C The expression level of ZNF24 and VEGFA was analyzed by immunohistochemistry (IHC) in the “ZNFTR-HIGH” or “ZNFTR-LOW” group. Forty-eight patients were separated into “HIGH” and “LOW” two groups according to the expression level of ZNFTR at the median. D Overall survival analysis in 48 patients with PC was shown by the Kaplan–Meier curve. Forty-eight patients were separated into “HIGH” and “LOW” two groups according to the expression level of ZNF24 at the median. E Schematic diagram of the mechanism by which ZNFTR regulated PC in normal and hypoxia environments.
