Fig. 6: TGM2 knock-down decreases oncogenic features in glioblastoma cell lines. | Cell Death & Disease

Fig. 6: TGM2 knock-down decreases oncogenic features in glioblastoma cell lines.

From: The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma

Fig. 6

A qRT-PCR analysis confirms siRNA-mediated knock-down of TGM2 in LN-229 and SF126 glioma cells. Shown are TGM2 mRNA levels normalized to PGK1 mRNA levels relative to control transfected cells set to 100%. Results of determination of cell viability using CellTiter-Glo assays (B), cell invasion using Boyden chamber assays (C), and colony formation propensity using colony formation assays (D) in control versus stable HOTAIRM1 knock-down LN-229 and SF126 cell lines. White bars represent control cells normalized to 100%, filled bars represent TGM2 knock-down cells. Two-way ANOVA was used for statistical analyses; mean ± SEM, ***p < 0.001, **p < 0.01. n = 3.

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