Fig. 2: Knockdown of CHPF inhibited proliferation and migration and promoted apoptosis of gastric cancer cells. | Cell Death & Disease

Fig. 2: Knockdown of CHPF inhibited proliferation and migration and promoted apoptosis of gastric cancer cells.

From: CHPF promotes gastric cancer tumorigenesis through the activation of E2F1

Fig. 2

A The effects of CHPF knockdown on AGS and SGC-7901 cells were detected by MTT assay. B The results show the effects of CHPF on the colony formation ability of gastric cancer cells. C The effects of CHPF knockdown on gastric cell apoptosis were evaluated by flow cytometry. D The differentially expressed proteins in gastric cancer cells between the shCHPF and shCtrl groups were identified by a human apoptosis antibody microarray. E The effects of CHPF knockdown on the migration ability of gastric cancer cells were examined by wound-healing assay (scale bar = 200 μm). Representative images were selected from at least three independent experiments. The data are expressed as mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001.

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