Fig. 1: The EV-mediated communication between PDAC and tumour microenvironment. | Cell Death & Disease

Fig. 1: The EV-mediated communication between PDAC and tumour microenvironment.

From: Extracellular vesicles in pancreatic cancer progression and therapies

Fig. 1

A PDAC-derived EVs contain various cargos that selectively modulate the surrounding cells types. B Different cell types exist in PDAC microenvironment and produce EVs with various contents that regulate PDAC progression. PDAC pancreatic ductal adenocarcinoma, PSC pancreatic stellate cell, TAM tumour-associated macrophage, CAF cancer-associated fibroblast, BM-MSC bone marrow-derived mesenchymal stem cell, NK natural killer cell, DC dendritic cell.

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