Fig. 1: Elevated expression of GOLPH3 is associated with the clinicopathologic characteristics of NSCLC. | Cell Death & Disease

Fig. 1: Elevated expression of GOLPH3 is associated with the clinicopathologic characteristics of NSCLC.

From: GOLPH3/CKAP4 promotes metastasis and tumorigenicity by enhancing the secretion of exosomal WNT3A in non-small-cell lung cancer

Fig. 1

a Analysis of GOLPH3 expression in a publicly available NSCLC dataset (NCBI/GEO/GSE75037). b Western blot analysis of GOLPH3 protein levels in the NLEC and NSCLC cell lines. c Quantification (top) and western blot analysis (bottom) of GOLPH3 protein expression in primary NSCLC tissues (T) and paired adjacent noncancerous lung tissues (N). Data represent the mean ± SD of three independent experiments. d IHC staining (left) and statistical analyses (right) of the average MOD of GOLPH3 expression in NSCLC specimens (magnification: upper ×200; lower ×400). Data represent the mean ± SD of three independent experiments; ***P < 0.001. e GOLPH3 overexpression correlates significantly with NSCLC clinical features (clinical stage, TNM classification, or survival). f Kaplan–Meier analysis of overall survival by GOLPH3 expression in NSCLC. g Spearman correlation analyses of GOLPH3 expression and clinical stage or TNM classification.

Back to article page