Fig. 5: miR-370-5P promoted the progression of HCC cells in vitro and in vivo. | Cell Death & Disease

Fig. 5: miR-370-5P promoted the progression of HCC cells in vitro and in vivo.

From: Circular RNA circUBE2J2 acts as the sponge of microRNA-370-5P to suppress hepatocellular carcinoma progression

Fig. 5

A, B The expression level of miR-370-5P in 40 TNBC tissues and their matched normal adjacent tissues was determined by qRT-PCR. C Overexpression and downregulation of miR-370-5P in hepatocellular carcinoma (HCC) cells using a miRNA-370-5P mimic or inhibitor, respectively, as measured by qRT-PCR. D miR-370-5P overexpression in MHCC97H and HLF cells promotes cell proliferation as measured by the CCK8 assay; downregulation of miR-370-5P in HepG2 cells inhibits cell proliferation as measured by the CCK8 assay. E The transwell assays. F The wound healing assays. G The expression levels of miR-370-5p were examined by qRT-PCR in HLF and MHCC97H cells with stable miR-370-5p overexpression. H, I HCC cells were subcutaneously injected into nude mice (H) and tumor volume were plotted (I). The data are represented as the mean ± SD, n = 3. *p < 0.05; **p < 0.01; NS no significance. m miR370-5P mimcs, mn mimcs nc, i miR370-5P inhibitor, in inhibitor nc.

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