Fig. 6: Overexpression of HCG15 aggravated cardiac IR injury. | Cell Death & Disease

Fig. 6: Overexpression of HCG15 aggravated cardiac IR injury.

From: Loss of exosomal LncRNA HCG15 prevents acute myocardial ischemic injury through the NF-κB/p65 and p38 pathways

Fig. 6

A ECG of mice in response to cardiac IR. B Representative images of Evans blue and triphenyl tetrazolium chloride (TTC) double-stained myocardial sections from mice at 4 weeks after cardiac IR; scale bar = 2 mm. C Myocardial IS in the indicated groups at 4 weeks after surgery; n = 5 per group, **p < 0.05. D Representative images of Masson staining of ventricular sections from mice at 4 weeks after cardiac IR and quantitative analyses of infarct size; scale bar = 1 mm; n = 5 per group, **p < 0.05. E–I Representative images of M-mode echocardiography (E) and relative indices of LVEDD (F), LVESD (G), LVEF (H), and LVFS (I) in mice at 4 weeks after cardiac IR, n = 5 per group, **p < 0.05. NF-κB antagonist (SN50); p38 MAPK antagonist (ralimetinib (LY2228820) dimesylate); (RA: ralimetinib (LY2228820) dimesylate).

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