Fig. 2: Mechanisms of NET effects on wound healing. | Cell Death & Disease

Fig. 2: Mechanisms of NET effects on wound healing.

From: The emerging roles of neutrophil extracellular traps in wound healing

Fig. 2

Excessive amounts of NET components such as neutrophil elastase, MPO, and MMPs can destroy wound structures, including collagen, fibronectin, and cellular matrix. In addition, NETs impair angiogenesis in the wound area. NETs also affect the number or functions of wound-repairing cells, eventually leading to delayed wound healing.

Back to article page