Fig. 1: IKBKBAS is upregulated both in LUAD tissues and cells along with the upregulation of IKKβ and activation of NF-κB. | Cell Death & Disease

Fig. 1: IKBKBAS is upregulated both in LUAD tissues and cells along with the upregulation of IKKβ and activation of NF-κB.

From: Novel cytoplasmic lncRNA IKBKBAS promotes lung adenocarcinoma metastasis by upregulating IKKβ and consequential activation of NF-κB signaling pathway

Fig. 1

A Validation and correlation of the IKBKBAS and IKKβ expression in LUAD specimens compared to their adjacent normal tissues by qRT-PCR analysis. B Partial results of western blotting on IKKβ expression in LUAD tissues compared to their adjacent normal tissues. C Basal expression of IKBKBAS and IKKβ in LUAD cell lines A549, H1299, H1650, HCC827, and normal cell lines BEAS-2B examined by qRT-PCR analysis. D Basal expression of IKBKBAS in LUAD cell lines A549, H1299, H1650, HCC827, and normal cell lineBEAS-2B examined by northern blotting. E Basal expression of IKKβ in LUAD cell lines A549, H1299, H1650, HCC827, and normal cell line BEAS-2B examined by western blotting. F Basal NF-κB activity in LUAD cell lines A549, H1299, H1650, HCC827, and normal cell line BEAS-2B showed by EMSA. G Luciferase reporter assay performed in LUAD cell lines A549, H1299, H1650, HCC827, and normal cell line BEAS-2B. Data show mean ± S.E.M., n ≥ 3, *P < 0.05, **P < 0.01, ***P < 0.01.

Back to article page