Fig. 1: Nrmt1−/− mice have enlarged lateral ventricles and reduced striatal volume. | Cell Death & Disease

Fig. 1: Nrmt1−/− mice have enlarged lateral ventricles and reduced striatal volume.

From: Age-related neurodegeneration and cognitive impairments of NRMT1 knockout mice are preceded by misregulation of RB and abnormal neural stem cell development

Fig. 1

a–d Cresyl violet staining showing Nrmt1−/− mice have enlarged lateral ventricles (black arrow heads) by 6 weeks that persist through 6 months. Quantification of e lateral ventricle, f whole brain, g cortex (cor), and h striatum (st) volume. *p < 0.05, **p < 0.005, ***p < 0.0005, and ****p < 0.0001 as determined by unpaired t-test, n = 3. Error bars represent mean ± SEM. Scale bar = 2 mm.

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