Table 1 Clinical characteristics of the patients with DN and the patients with minor lesions who did not have diabetes.

From: Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy

 

Control

DN

p

BMI (kg/m2)

23.1 ± 3.1

24.7 ± 4.2

0.25

Blood glucose (mmol/L)

4.68 ± 0.52

8.6 ± 0.23

<0.0001

HBA1c (%)

4.75 ± 0.46

8.2 ± 0.53

<0.0001

Total cholesterol (mmol/L)

6.31 ± 0.14

7.24 ± 0.19

<0.0001

Triglyceride (mmol/L)

2.65 ± 0.38

4.22 ± 1.6

0.0009

LDL (mmol/L)

2.1 ± 0.64

2.9 ± 0.88

0.0082

ALT (IU/L)

18.3 ± 4.3

17.8 ± 5.4

0.7811

AST (IU/L)

24.1 ± 8.7

23.8 ± 7.67

0.9209

Albumin (g/L)

39.1 ± 3.5

32.3 ± 1.9

<0.0001

BUN (mmol/L)

5.81 ± 0.41

6.03 ± 0.22

0.07777

Scr (μmol/L)

92.4 ± 8.9

95.17 ± 7.54

0.3656

UA (μmol/L)

346 ± 67

409 ± 83

0.0299

Urine protein (g/24 h)

3.14 ± 1.31

4.38 ± 1.09

0.0088

Red blood cells count in urine sediment(/mL)

15010 ± 998

11003 ± 1034

<0.0001

Systolic pressure (mmHg)

119.12 ± 4.5

148.19 ± 2.5

<0.0001

Diastolic pressure (mmHg)

82.14 ± 1.67

96.13 ± 2.07

<0.0001

  1. Values are the mean ± SD.
  2. HBA1c glycosylated hemoglobin, LDL low-density lipoprotein, ALT alanineaminotransferase, AST aspartate aminotransferase, BUN blood urea nitrogen, Scr serum creatinine, UA uric acid.