Table 2 Characteristics of the different groups’ mice.

From: Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy

Group

db/m

db/db Cont

db/db+ AdipoRon

p*

p#

n

12

12

12

  

Body weight (g)

29.8 ± 1.5

53.3 ± 5.2

51.5 ± 3.2

<0.0001

0.4531

Kidney weight (mg)

203 ± 5.8

204.7 ± 7.3

203 ± 9.2

0.8471

0.8471

Blood glucose (mmol/L)

8.5 ± 0.5

29.89 ± 3.6

21.7 ± 3.7

<0.0001

<0.0001

HbA1c (%)

4.1 ± 0.2

9.2 ± 0.4

8.6 ± 0.1

<0.0001

<0.0001

Triglyceride (mmol/L)

0.98 ± 0.2

1.96 ± 0.2

1.63 ± 0.3

<0.0001

0.0017

Total cholesterol (mmol/L)

1.43 ± 0.2

3.46 ± 0.3

3.2 ± 0.4

<0.0001

0.13

Scr (ÎĽmol/L))

16.6 ± 2.9

19.1 ± 3.6

17.8 ± 3.3

0.1641

0.6

24 h albuminuria (mg/day)

10.17 ± 1.7

222.8 ± 35.2

157.4 ± 20.7

<0.0001

<0.0001

Serum adiponectin (ÎĽg/mL)

10.9 ± 0.8

4.6 ± 0.4

4.7 ± 0.5

<0.0001

0.9156

  1. Values are the mean ± SD.
  2. p*: db/m versus db/db; p#: db/db versus db/db + AdipoRon.
  3. HBA1c glycosylated hemoglobin, Scr serum creatinine.