Table 2 Characteristics of the different groups’ mice.
Group | db/m | db/db Cont | db/db+ AdipoRon | p* | p# |
---|---|---|---|---|---|
n | 12 | 12 | 12 | Â | Â |
Body weight (g) | 29.8 ± 1.5 | 53.3 ± 5.2 | 51.5 ± 3.2 | <0.0001 | 0.4531 |
Kidney weight (mg) | 203 ± 5.8 | 204.7 ± 7.3 | 203 ± 9.2 | 0.8471 | 0.8471 |
Blood glucose (mmol/L) | 8.5 ± 0.5 | 29.89 ± 3.6 | 21.7 ± 3.7 | <0.0001 | <0.0001 |
HbA1c (%) | 4.1 ± 0.2 | 9.2 ± 0.4 | 8.6 ± 0.1 | <0.0001 | <0.0001 |
Triglyceride (mmol/L) | 0.98 ± 0.2 | 1.96 ± 0.2 | 1.63 ± 0.3 | <0.0001 | 0.0017 |
Total cholesterol (mmol/L) | 1.43 ± 0.2 | 3.46 ± 0.3 | 3.2 ± 0.4 | <0.0001 | 0.13 |
Scr (μmol/L)) | 16.6 ± 2.9 | 19.1 ± 3.6 | 17.8 ± 3.3 | 0.1641 | 0.6 |
24 h albuminuria (mg/day) | 10.17 ± 1.7 | 222.8 ± 35.2 | 157.4 ± 20.7 | <0.0001 | <0.0001 |
Serum adiponectin (μg/mL) | 10.9 ± 0.8 | 4.6 ± 0.4 | 4.7 ± 0.5 | <0.0001 | 0.9156 |