Fig. 1: Ionizing radiation inhibits the proliferation of breast cancer cells. | Cell Death & Disease

Fig. 1: Ionizing radiation inhibits the proliferation of breast cancer cells.

From: Ionizing radiation downregulates estradiol synthesis via endoplasmic reticulum stress and inhibits the proliferation of estrogen receptor-positive breast cancer cells

Fig. 1

MCF7, T47D, and MDA-MB-231 cells were irradiated with X-rays at different doses. The morphology of MCF7 and MDA-MB-231 cells became swollen after irradiation at 24 h (A). Cellular proliferation (B) and clonal formation (C, D) of MCF7 and T47D cells were inhibited by radiation in dose- and time-dependent manners. Malignant proliferation decreased after 2 Gy of radiation in MCF7 tumor cells (E) (mean ± SD of triplicate assessments, Student’s t-test, **p < 0.01).

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