Fig. 4: A positive correlation exists between ARSD and FOXA1, GATA3 or ESR1, respectively. | Cell Death & Disease

Fig. 4: A positive correlation exists between ARSD and FOXA1, GATA3 or ESR1, respectively.

From: ARSD, a novel ERα downstream target gene, inhibits proliferation and migration of breast cancer cells via activating Hippo/YAP pathway

Fig. 4

A–C qRT-PCR results reveal that ectopically overexpressing FOXA1, GATA3, and ESR1 significantly upregulate ARSD expression level, respectively. D, E Western blotting results reveal that ectopically overexpressing FOXA1, GATA3, and ESR1 significantly upregulates ARSD protein level, respectively. F Pearson correlation between the gene expression of ARSD and luminal subtype transcriptional factors, e.g., FOXA1, GATA3, ESR1, SPDEF, wtTP53, and PPARG in breast cancer. Data was adopted from the Gene Expression Profiling Interactive Analysis (GEPIA) resource. G Visualizing the correlation matrix as a heatmap.

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