Fig. 4: Cpeb3 mutation affects granulosa cells apoptosis and proliferation. | Cell Death & Disease

Fig. 4: Cpeb3 mutation affects granulosa cells apoptosis and proliferation.

From: CPEB3 deficiency in mice affect ovarian follicle development and causes premature ovarian insufficiency

Fig. 4

A Apoptosis of ovaries was assessed by TUNEL assay at 3-month-old ovaries. B Representative micrographs of follicles stained for Cleaved-Capase3 at 3-month-old ovaries. C, D Ovarian sections stained for PCNA and pHIS3 at 3-month-old ovaries. The number of results was accounted for per developing follicle. Scale bar = 161 μm and 64 μm in A; 100 μm and 50 μm in B–D. Data were represented as the mean ± SD ****P < 0.0001.

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