Table 1 Cpeb3 mutation females were subfertile.

From: CPEB3 deficiency in mice affect ovarian follicle development and causes premature ovarian insufficiency

Genotype

Total females

Pregnant females

Pregnant ratio

Total no. of pups

Total litters

Average no. of pups/ litter

WT

9

9

100%

334

41

8.146 ± 1.805

Cpeb3 mut

9

5

55.5%

73

13

5.615 ± 1.636****

  1. WT and Cpeb3-mutant female mice of 3-month-old were mated with WT 2–3-month-old C57BL/6 J male mice that had proven normal fecundity until the female mice were 9-month-old. Female mice with vaginal plug and later visibly growing abdomen were included in this assessment. The numbers of pups per litter or pups (both alive and dead) were assessed. Data were represented as the mean ± SD. ****P < 0.0001.
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