Fig. 5: Human and murine melanoma cells release vesicles upon stimulation of P2X7R.

Representative images acquired with a confocal microscope of A Sk-Mel-28 cells, B Ma-Mel-19 cells, and C B16-F10 cells before and after stimulation with the P2X7 agonist BzATP (500 μM). The plasma membrane was stained with the red dye PKH26GL, while nucleic acid content was labeled with quinacrine.