Fig. 8: FUT8 negatively regulates NF-κB2 signaling by blocking the activation of TNFR.

A Immunohistochemical staining of FUT8, FADD, NFκB2, BCL2A1, and cleaved-caspase 3 in xenografts of OS tissue from the subcutaneous tumor nude mouse model visualized by DAB. B Diagram illustrating one mechanism that illustrates how FUT8 influences OS cell apoptosis through the TNF/NFκB signaling pathway.