Fig. 1: Histology characteristics and MRI images of diffuse low-grade glioma and high-grade glioma. | Cell Death & Disease

Fig. 1: Histology characteristics and MRI images of diffuse low-grade glioma and high-grade glioma.

From: Current landscape of tumor-derived exosomal ncRNAs in glioma progression, detection, and drug resistance

Fig. 1

A Diffuse low-grade astrocytoma is composed of mutated astrocytes uniformly infiltrating around the brain tissues. The tumor cells show less nuclear atypia and slower proliferation. B The mass, in the temporal lobe, has isosignal and low intensity on T1-weighted imaging and shows mixed high and low signals on T2-weighted imaging. C Anaplastic astrocytomas show nuclear atypia and greater proliferative capacity, with nearby erythrocyte infiltration. D The occupied mass, in the temporal lobe, shows low intensity on T1-weighted imaging and high signals on T2-weighted imaging with irregular margins. E GBM shows apparent nuclear atypia and prodigious proliferation. F The tumor is located in the parietal lobe, with annular high intensity and central low intensity on T1-weighted imaging and mixed signals and peripheral edema signal on T2-weighted imaging. Tumor cell is dividing and duplicating their chromosomes (showing with arrows). Tumor cells masquerade as endothelial cells (showing in boxes). H&E, ×200, bar = 100 microns. GBM Glioblastoma multiforme.

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