Table 1 Correlation between the clinicopathologic factors and expression of HMGA1 and MYH9 in glioma.

From: HMGA1 stimulates MYH9-dependent ubiquitination of GSK-3β via PI3K/Akt/c-Jun signaling to promote malignant progression and chemoresistance in gliomas

Factors

n

HMGA1 expression (%)

MYH9 expression (%)

High

Low

P

High

Low

P

Tumors and normal samples

Tumors

86

48

38

0.01

49

37

0.008

Normal brain tissues

15

3

12

4

11

Gender

Male

57

35

22

0.143

36

21

0.105

Female

29

13

16

13

16

Age

≥50

36

25

11

0.031

26

10

0.015

<50

50

23

27

23

27

Histologic type

DA

28

9

19

<0.001

7

21

<0.001

OD

11

3

8

4

7

AA

14

10

4

10

4

GBM

33

26

7

28

5

WHO grade

II

39

12

27

<0.001

11

28

<0.001

III

14

10

4

10

4

IV

33

26

7

28

5

  1. DA diffuse astrocytoma, OD oligodendroglioma, AA anaplastic astrocytoma, GBM glioblastoma.
  2. Bold values indicates statistically significant P < 0.05 values.
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