Table 2 Summary of univariate and multivariate Cox regression analysis of overall survival duration.

From: HMGA1 stimulates MYH9-dependent ubiquitination of GSK-3β via PI3K/Akt/c-Jun signaling to promote malignant progression and chemoresistance in gliomas

Factors

Number

Univariate analysis

Multivariate analysis

P

Hazard ratio

95% confidence interval

P

Hazard ratio

95% confidence interval

Gender

Male vs. female

57 vs. 29

0.205

0.147

0.103–0.406

   

Age group

<50 vs. ≥50

50 vs. 36

0.026

1.977

1.083–3.607

   

WHO grade

II vs. III vs. IV

39 vs. 14 vs. 33

<0.001

3.382

2.279–5.020

0.001

2.212

1.397-3.505

Pathological diagnosis

DA vs. OD vs. AA vs. GBM

28 vs. 11 vs. 14 vs. 33

<0.001

2.418

1.777–3.288

   

HMGA1 expression

High vs. low

48 vs. 38

<0.001

7.568

3.191–17.948

0.002

4.290

1.713-10.744

MYH9 expression

High vs. low

49 vs. 37

<0.001

7.687

3.369–17.539

<0.001

5.572

2.243-13.839

  1. DA diffuse astrocytoma, OD oligodendroglioma, AA Anaplastic astrocytoma, GBM glioblastoma.
  2. Bold values indicates statistically significant P  <  0.05 values.
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