Fig. 1: CD82 expression was down-regulated in retina, ONH, and ON in the early stage after acute IOP hypertension. | Cell Death & Disease

Fig. 1: CD82 expression was down-regulated in retina, ONH, and ON in the early stage after acute IOP hypertension.

From: CD82 protects against glaucomatous axonal transport deficits via mTORC1 activation in mice

Fig. 1

a Immunostaining of CD82 in mouse retina, ON, ONH at 8 h, 1d, 2d, 3d, 7d after inducing AOHT, n = 5 eyes for each group. Scale bar, 50 μm. b Western blot showing protein levels of CD82 in mouse retina, ON, and ONH tissues at 8 h, 2d, 7d after AOHT. c−e Statistical analysis of the data shown in (b) from retina (c), ON (d), and ONH (e). The data were expressed as mean ± S.E.M., n = 4, one-way ANOVA **P < 0.01, ***P < 0.001. Co-immunofluorescent staining of CD82 (red) with RGC marker Tuj1 (green) (f), microglia marker Iba1 (green) (g), astrocyte marker (GFAP) (h) in mouse retina, ON, ONH in sham and 2d post-AOHT groups, n = 4 eyes for each group. Scale bars, 50 μm.

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