Fig. 8: Schematic representation of CD82 neuroprotection effect after ocular hypertension.
From: CD82 protects against glaucomatous axonal transport deficits via mTORC1 activation in mice
Acute ocular hypertension induced axonal transport deficits and subsequently caused axon degeneration. CD82 overexpression protected against axon injury through upregulating TRAF2, which activates mTORC1 through K63-linked ubiquitylation and intracellular repositioning of Raptor.
