Fig. 5: miR-411-5p mediates the oncogenic effects of KDM4A-AS1 on HCC cells. | Cell Death & Disease

Fig. 5: miR-411-5p mediates the oncogenic effects of KDM4A-AS1 on HCC cells.

From: HIF-1α-activated long non-coding RNA KDM4A-AS1 promotes hepatocellular carcinoma progression via the miR-411-5p/KPNA2/AKT pathway

Fig. 5

Hep3B cells with KDM4A-AS1 overexpression were transfected with miR-411-5p mimics or control, while SK-Hep-1 cells with KDM4A-AS1 knockdown were transfected with miR-411-5p inhibitors or control. A CCK-8, B Edu (scale bars = 20 μm), C colony formation, D transwell (scale bars = 100 μm), and E western blotting assays were conducted to examine the proliferation, migration, invasion, and EMT process of HCC cells in different groups. Scale bar: 20 μm for Edu results and 100 μm for transwell results. *P < 0.05.

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