Fig. 7: Upstream activator of autophagy cannot improve P62 accumulation induced by Sidt2 knockout. | Cell Death & Disease

Fig. 7: Upstream activator of autophagy cannot improve P62 accumulation induced by Sidt2 knockout.

From: Sidt2 is a key protein in the autophagy-lysosomal degradation pathway and is essential for the maintenance of kidney structure and filtration function

Fig. 7

A Changes of key autophagy proteins in MPC5 cells on adding rapamycin; B statistical chart of (A); C P62 mRNA expression in MPC5 cells before and after adding rapamycin; D changes of key autophagy proteins in SV40 MES 13 cells on adding rapamycin; E statistical chart of (D); F P62 mRNA expression in SV40 MES 13 cells on adding rapamycin; *P < 0.05, **P < 0.01, ***P < 0.001.

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