Fig. 5: USP3 upregulates COL9A3 and COL6A5 to promote GC cells EMT, invasion and migration in vivo. | Cell Death & Disease

Fig. 5: USP3 upregulates COL9A3 and COL6A5 to promote GC cells EMT, invasion and migration in vivo.

From: USP3 promotes gastric cancer progression and metastasis by deubiquitination-dependent COL9A3/COL6A5 stabilisation

Fig. 5

A Tail vein injection with GC cells was performed in nude mice (n = 3 in each group). Images of metastatic loci in the lungs are shown. B The number of metastatic loci in the lungs was counted. C Metastatic cancer tissues were analysed by HE staining. D Vimentin and E-cadherin expression in the lung metastasis of GC was detected by IHC. The error bars represent the mean ± SD from three independent experiments. Scale bars, 200 μm in C and D.

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